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Home   /   Product   /   PVA Pharmaceutical Excipients

PVA Pharmaceutical Excipients

LIWEI CHEMICAL CO. LTD

Specifications

Appearance

 Polyvinyl Alcohol

Total Solids wt%(min)

9002-89-5

White to yellowish powder or translucent granule.
Medium soluble in ethanol, slightly soluble in acetone, almost insoluble in acetone. The solubility of PVA XX-88 model is relatively good in hot water and cold water.

 

Model

Model

Viscosity(mPa.S)

Grain Size

03-88

3.0-4.5

Granule

03-88

3.0-4.5

Powder

05-88

4.5-6.0

Granule

05-88

4.5-6.0

Powder

17-88

20-24

Granule

17-88

20-24

Powder

24-88

40-60

Granule

24-88

40-60

Powder

20-88

32

Granule

05-99

4.5-6.0

Granule

08-99

 

Granule

17-99

20-30

Granule

24-99

 

Granule

 

 

 

 


Packing & Storage

Packing

 5kg per bag, 20/25kg per drum Appearance:

Storage Powder 20°C 2 years; Floccule 20°C 2 years.
Shipping Room temperature 5-30℃ in China; may vary elsewhere
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Frequently Asked Questions

Product Feature:

This product is prepared by alcoholysis of polyvinyl acetate in methanol solution by adding alkali solution. The molecular formula is expressed by (CH2CHOH) n (CH2CHOCOCH3) m, where ‘m + n’ represents the average degree of polymerization, and m/n should be 0~0.35. The average molecular weight shall be 20000 ~ 150000.

There are many types of polyvinyl alcohol according to the degree of polymerization and alcoholysis. The common naming standard for product models is “polyvinyl alcohol xy-mn”, where xy represents the average degree of polymerization and mn represents the degree of alcoholysis. Our company mainly produces models with alcoholysis degree of 88%, including 03-88, 05-88, 17-88,24-88 and 20-88 models, and other models can be customized if necessary.

Application:

This product has good film-forming characteristics, and can be used as a film-forming material in film agents and film coating agents, and can also be used as a film-forming material in thin film; This product also has a good suspending effect. It can also be used as emulsifiers and emulsification stabilizers in o/w emulsions. It can also be used as thickening agents, lubricants and protective agents in some eye drops.This product also has gel-forming properties and is used in some gel dosage forms such as gel patches. It can be used as an adhesive for ordinary tablets, granules, etc.

Application Application Examples

As a film-forming material in coating agent/ spray agent/ film-coated agents As thickening agents, lubricants and suspending agents in eye drops
As binder in tablets and granules
Used in gel dosage forms due to gel-forming properties
As emulsifiers/emulsification stabilizers in o/w emulsions due to its good suspending effect As a coating material for food additives

Incompatibility:

Polyvinyl alcohol has various reactions of secondary hydroxyl compounds, such as esterification reaction. It will drop in strong acids, soften or dissolve in weak acids and alkalis. High concentrations of PVA is incompatibility with inorganic salts, especially sulphate and phosphate. Phosphate can precipitate 5% (W/V) of polyvinyl alcohol. Borax can make PVA forms a gel.

Safety:

This product is generally a non-toxic material. When the concentration is as high as 10%, it has no irritation to skin and eyes. Cosmetics can use polyvinyl alcohol with a concentration of up to 7%. Rat experiments show that subcutaneous injection of 5% (W/V) polyvinyl alcohol can cause anemia.

Storage:
Stored in a cool, dry and sealed container.

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