Polyvinyl alcohol (PVA) is a stable, non-toxic, water-soluble polymer obtained by the polymerization and alcoholysis of vinyl acetate. PVA molecules contain numerous hydroxyl groups, which can form a physical cross-linked network through hydrogen bonding and van der Waals forces. After treatment with methods such as cyclic freeze-thaw cycles, it exhibits rubber-like elasticity and excellent mechanical properties. Its tensile strength, compressive strength, flexibility, and ductility are far superior to most hydrogel materials, making it an ideal flexible substrate material widely used in wearable devices, implantable medical devices, tissue engineering, and composite hydrogels.
Yuanzheng Biotech's PVANB is a photosensitive functionalized biomaterial that introduces o-nitrobenzyl alcohol (NB) groups into the PVA molecule. It retains the excellent mechanical properties and biocompatibility of PVA while adding photoresponsive cross-linking and bio-coupling capabilities, making it one of the core raw materials for constructing high-strength, functionalized hydrogels and bio-interfaces.
PVANB can be used in combination with biopolymers containing methacrylamide groups (such as HAMA and CMCMA). Under the action of a photoinitiator and light irradiation, PVANB can rapidly undergo copolymerization and cross-linking, forming a high-strength hydrogel network within seconds. Furthermore, based on the aldehyde groups released by PVANB photolysis, it can also covalently couple with amino-containing biomolecules (such as proteins, peptides, drugs, and active factors), achieving precise modification and enhancement of the hydrogel's biological functions.
PVANB Molecular Structure Diagram
I. Product Catalog
Yuanzheng Biotechnology's PVANB products are offered with ultra-low impurity levels, stable quality, and are suitable for biomedical and flexible device applications.
Note: Products are available in various specifications such as 1 g/vial, 2 g/vial, and 5 g/vial, and customized production is supported according to customer needs.
II. Product Features
1. Rapid Photocrosslinking Molding: Seconds-level curing forms a high-strength, tough hydrogel with excellent mechanical properties.
2. Tissue Adhesion and Integration: Photolysis releases aldehyde groups that covalently bind to amino groups on the tissue surface, achieving strong adhesion.
3. Biomolecular Coupling Platform: Aldehyde groups can be used to immobilize active molecules such as proteins, peptides, and drugs, expanding the hydrogel's functionality.
4. Excellent Flexibility and Biocompatibility: The PVA substrate possesses good flexibility, processability, and biocompatibility.
III. Typical Applications
1. Flexible Bioelectronic Devices: As a flexible substrate material, used in wearable sensors, implantable medical devices, etc.
2. Tissue Engineering Scaffolds: Constructing high-mechanical-performance hydrogel scaffolds for soft tissue repair such as cartilage and skin.
3. Drug Controlled Release Systems: Developing in-situ gel systems with adhesive properties to achieve localized sustained drug release.
4. Biointerface Modification: Modifying material surfaces through photocoupling reactions introduces bioactivity and improves cell behavior.
IV. Product Advantages
1. High Batch Consistency: Standardized production processes ensure stable and reliable product performance;
2. Ultra-High Purity and Low Residue: Special purification processes effectively remove small molecule residues of NB, ensuring biosafety;
3. Strict Quality Control System: Each batch of products undergoes rigorous testing to ensure compliance with research and development requirements;
4. Flexible Customization Services: Supports customized and large-scale supply of products with different specifications and performance parameters.
Website: www.china-pva.net
Whatsapp: 0086-15380400285
E-mail: sales2@china-pva.net
